If you're over 60 and tossing and turning at night, it’s easy to blame stress, aging, or even too many naps. But have you looked inside your medicine cabinet lately?
Many older adults struggle with poor sleep and don’t realize that some of their everyday medications may be quietly interfering with their rest.
In fact, according to AARP, several commonly prescribed medications can cause or worsen insomnia, making it harder to fall asleep, stay asleep, or feel rested in the morning.
Let’s break it down.
Medications That Can Cause Sleep Problems
As we age, we're more likely to be prescribed medications for chronic conditions like high blood pressure, arthritis, and mood disorders. But some of these same drugs can come with a hidden side effect: disrupted sleep.
Here are 10 sleep-disrupting drugs often used by older adults:
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Corticosteroids (e.g., prednisone) – used for inflammation or autoimmune diseases
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Beta-blockers – prescribed for heart conditions and high blood pressure
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SSRIs (like sertraline or fluoxetine) – used to treat depression and anxiety
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Statins – cholesterol-lowering medications
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Decongestants – found in cold and allergy medications (especially pseudoephedrine)
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Diuretics – “water pills” that may cause nighttime trips to the bathroom
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Stimulants – sometimes prescribed for ADHD or excessive daytime sleepiness
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Alzheimer’s medications – like donepezil, which may increase nighttime awakenings
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Thyroid medications – can lead to a revved-up metabolism if taken too late in the day
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Certain pain medications – especially those containing caffeine or that cause rebound discomfort at night
You can find the full list and more detail in the original AARP article here.
Why Sleep Is So Important After 60
Sleep is when the body repairs, restores, and resets. After 60, getting consistent, good-quality sleep is linked to better memory, immune function, mood, and even a lower risk of heart disease and dementia.
But when your sleep gets interrupted by side effects—like waking up to use the bathroom, feeling restless, or not being able to wind down—your sleep quality suffers, even if you're “in bed” for 8 hours.
Not All Sleep Problems Are “Just Aging”
Too often, older adults are told that waking up multiple times at night is just a “normal part of aging.” While some changes in sleep architecture are expected, persistent sleep issues could point to something treatable—like a medication side effect, sleep apnea, or even lifestyle factors.
That’s why it’s so important to review your medications regularly—with your doctor or pharmacist—especially if your sleep has taken a hit.
What You Can Do to Protect Your Sleep
If you’re taking any of the medications mentioned and noticing poor sleep, don’t stop them on your own. Instead:
✅ Talk to your healthcare provider – They may be able to adjust the timing, dosage, or switch to an alternative.
✅ Avoid stimulating medications before bedtime – Some drugs are best taken in the morning.
✅ Watch for drug interactions – Especially if you’re taking over-the-counter sleep aids or supplements.
✅ Build sleep-friendly habits – Like limiting caffeine, getting morning sunlight, and creating a consistent bedtime routine.
✅ Don’t underestimate the impact of naps – Done right, they can refresh you. Done wrong, they can ruin your night’s sleep.
Check out this guide: How to Nap Without Ruining Your Sleep
For Caregivers: A Quick Word
If you're caring for an older adult who seems more tired during the day but restless at night, take a close look at their medication list. Many sleep complaints in older adults get brushed off—but they might be easier to address than you think.
Sleep isn’t just a luxury—it’s essential to healthy aging. And sometimes, the key to better sleep is simply knowing where to look. Medications that disrupt sleep are more common than most people realize, but with the right support and adjustments, you (or your loved one) can get back to more restful nights.
If you found this helpful, share it with a friend or bring it up at your next doctor’s visit. You deserve good sleep—at every age.